No. 1 Duke vs. No. 16 North Florida or Robert Morris
Duke has earned the top seed in the South Region.
The Blue Devils (29-4) will play their NCAA Tournament opener Friday in Charlotte against the winner of a First Four matchup between North Florida and Robert Morris.
Duke is making its 20th straight NCAA Tournament appearance and is chasing its fifth national title and 12th berth in the Final Four under Mike Krzyzewski. The Blue Devils finished second in the Atlantic Coast Conference and lost to Notre Dame in the ACC Tournament semifinals.
Robert Morris (19-14) earned its eighth Northeast Conference tournament title and is in the tournament for the first time since 2010.
North Florida (23-11) earned its first NCAA Tournament berth by winning the Atlantic Sun Tournament.
No. 2 Gonzaga vs. No. 15 North Dakota State
Gonzaga earned the No. 2 seed in the NCAA South Region and will open play against No. 15 seed North Dakota State.
The teams meet Friday in Seattle, giving the Zags (32-2) the chance to play in their home state.
Gonzaga was in contention for a No. 1 seed for much of the season thanks to its strong offense led by Kyle Wiltjer (16.7 points), then won the West Coast Conference Tournament for the third straight season. Gonzaga shot a national-best 52.4 percent and is in its 17th straight NCAA Tournament appearance.
North Dakota State (23-9) won the Summit League title for its second straight NCAA trip. The Bison are led by senior guard Lawrence Alexander, who averaged 18.9 points and shot 44 percent from 3-point range.
No. 3 Iowa State vs. No. 14 UAB
Iowa State has earned the No. 3 seed in the South Region.
The two-time Big 12 Tournament champion Cyclones (25-8) will open NCAA Tournament play on Thursday in Louisville against 14th-seeded UAB (19-15).
The Cyclones are in the tournament for the fourth straight year under coach Fred Hoiberg. They rallied from 17 points down to beat Kansas in the Big 12 final on Saturday.
The Blazers won their first Conference USA Tournament and made it into the bracket for the first time since 2011.
Coach Jerod Haase said earning an NCAA Tournament berth is "a rallying cry" for a school that has faced criticism from fans and students for dropping its football program.
No. 4 Georgetown vs. No. 13 Eastern Washington
Georgetown has earned the No. 4 seed in the NCAA South Region and will open play against No. 13 seed Eastern Washington.
The teams meet Thursday in Portland.
The Hoyas (21-10) were ranked No. 23 in the Top 25 and reached the semifinals of the Big East Tournament before falling to Xavier on Saturday. Georgetown is led by D'Vauntes Smith-Rivera, who is averaging 16.2 points per game.
Eastern Washington earned its second NCAA bid by rallying from 11 down to beat Montana in the Big Sky Tournament championship game. The Eagles (26-8) last went to the NCAA Tournament in 2004.
Eastern Washington is led by high-scoring junior Tyler Harvey, who is averaging 22.9 points per game.
No. 5 Utah vs. No. 12 Stephen F. Austin
Utah is back in the NCAA Tournament, earning the No. 5 seed in the South Region against an opponent that knows how to pull off an upset.
The Utes (24-8) will play their tournament opener on Thursday in Portland against 12th-seeded Stephen F. Austin (29-4).
Utah is making its 28th NCAA Tournament appearance but first since 2009 and first as a member of the Pac-12 Conference. The Utes were knocked out of the Pac-12 Tournament in the semifinals when Oregon hit a buzzer-beater to win 67-64.
Stephen F. Austin won its second straight Southland Conference Tournament title, beating Sam Houston State in the final for the second consecutive year.
The Lumberjacks were a No. 12 seed last year when they upset fifth-seeded VCU before falling to UCLA.
No. 6 SMU vs. No. 11 UCLA
Larry Brown is back in the NCAA Tournament.
The coach who led Kansas to the 1988 national title has guided SMU to the No. 6 seed in the South Region.
The Mustangs (27-6) will play their tournament opener Thursday in Louisville against 11th-seeded UCLA (20-13).
SMU won the American Athletic Conference Tournament earlier Sunday by beating defending national champion Connecticut in the final to earn its first league championship since 1988 in the Southwest Conference. The Mustangs are in the tournament for the first time since 1993.
UCLA won 12 of its last 17 games under coach Steve Alford but was considered on the tournament bubble after its loss to Arizona in the Pac-12 Tournament semifinals.
No. 7 Iowa vs. No. 10 Davidson
Iowa has earned the No. 7 seed in the NCAA South Region and will open play against No. 10 seed Davidson.
The teams meet Friday in Seattle.
Iowa (21-11) reached 20 wins for the third straight season. Senior forward Aaron White led the Hawkeyes in scoring (16 points) and rebounding (7.5).
Iowa is making its second straight NCAA trip and its fourth straight postseason appearance overall.
Davidson (24-7) made a surprise run to the Atlantic 10 regular-season title under coach Bob McKillop. Led by league player of the year Tyler Kalinoski, the Wildcats were one of the nation's best 3-point shooting teams and led the nation in assist-to-turnover margin entering the postseason.
Davidson is in the NCAAs for the seventh time since 2002, but this is its first at-large bid.
No. 8 San Diego State vs. No. 9 St. John's
St. John's would likely earn a rematch with Duke if the Red Storm can get past San Diego State in their NCAA Tournament opener.
San Diego State (26-8) earned the No. 8 seed in the South Region and will begin tournament play Friday in Charlotte against the ninth-seeded Red Storm (21-11).
A win by St. John's would almost certainly set up another matchup with the top-seeded Blue Devils. The Red Storm blew a double-digit lead in the second half in January and lost to them, giving Mike Krzyzewski his 1,000th career win.
The Red Storm flamed out of the Big East tournament early when Providence routed them 74-57 in the quarterfinals.
San Diego State was upset in the Mountain West final by Wyoming, but earned their sixth straight NCAA berth.