Thomas left New Orleans' game against Atlanta early last Sunday with an injury to his ribs. Hicks has been limited in practice prior to this week with an ankle injury.
Thomas is third on the team with 222 yards rushing and two touchdowns. He also has 378 yards receiving and another score.
Hicks, meanwhile, has 58 tackles, two sacks and two passes defensed.
Coach Sean Payton said it was unlikely for either Coleman or Franklin to play against the Buccaneers.